zankaon

July 28, 2014

EBOLA

Ebola fever seems to be endemic in West African cities, and epidemic in how many countries? (1) Can it easily spread to the Americas and Europe via air transport? Are we potentially on the verge of a world wide epidemic, more rapidly spreading than AIDs? Or would current public health measures suffice to protect us?

It seems to be more communicable than AIDs, in that bodily fluids in general can apparently easily spread the virus. Is communicability of the virus in part via saliva, and then wiped on to one’s face, hands, and arms? Or is it just another enteric fever? ls this partially how health care workers are exposed? Is there an earlier cough or sneeze respiratory component involved? Are children, teenagers, and young adults also infected; also equally for women?

If it is an enteric fever, then fecal oral spread etc., would necessitate public health sanitation measures, irregardless of social issues. For examble, more portable, and not, latrines, and other intermediate term public sanitation methods.

If it is just an enteric fever, then perhaps it requires just keeping up with fluids, in order to prevent hypovolemic shock, and resultant organ shut down.

Can the immune system (serum, lymphoid) of children be studied, if they are immune? Or has (is) the virus mutating i.e. adapting, in such incubator environment? Vaccine possibilities? If the above are immune, can they perhaps be enlisted as healthcare workers?

Might essentially (?) the non-involvement of children, and women, suggest, at least for the former, the importance of innate immunity, rather than adaptive immunity? Might innate immune response assume more importance for youth, since the adaptive immune system has not yet built up a set of exposures (and secondary response) to microbes?  Perhaps research attention could be directed toward ways of boosting such innate immunity, such as some sort of generic adjuvent therapy, or agonist, allosteric, enhancer, epigenetic effect. Or perhaps instigate a rapid onset minor infection in order to stimulate an innate (toll receptors?) response – a new early responder approach to viral immunity?

Can asymptomatic persons still be infectious, not unlike some other communicable viruses? Might contingency plans by American CDC, such as quarantine facilities for near to major entry points, be necessary? Thus apparent sick people, if coming off planes, have to prove that they do not harbor Ebola. What is the incubation period? Also more funding for robotic laboratories, with assistance from younger workers, if immune?

In addition to sanitation measures, might ultraviolet skin photo treatment (uv booths) both for health workers, patients etc. eliminate such virus temporarily from the skin; thus prevention in part, inclusive of lessening the communicable risk?

1. World Health Organization

chance favors the prepared mind

Louis Pasteur

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