Restricted diet seems to prolong lifespan in C. elegans, like for other species tested. But what about functionality for such aged nematodes? Might enhanced activity further prolong lifespan, and also preserve functionality? More specifically, perhaps have a medium of reduced nutrient, but with more gel mixed in (greater density), so as to require more effort (proxy for exercise). Might any suitable proxy for increased exercise in other species, further extend lifespan? Or might it just help to preserve functionality, when compared to controls? That is, does additional exercise preserve normal loco-motor activity in aged C. elegans, as observed and/or measured per microscope?
February 16, 2013
Functionality (activity) in aging C. elegans
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